Antiplasmodial activities of leaves and trunk bark of Sclerocaria Birea (A. Ric H.) Hochst (Anacardiaceae), a plant used in traditional medicine of Niger

In the crude extracts of bark and leaves Sclerocarya birrea, have been characterized sterols, triterpenes, saponosides, tannins, anthocyanosides, coumarins, reducing compounds, alkaloids carotenoids. Tests were carried out in vitro with from each part plant to assess their efficacy against strains Plasmodium falciparum sensitive chloroquine K1 that resistant 3D7. The alkaloidal gave IC50 = 2.54 μg / ml strain 3D7 an 4.09 K1. On other hand, CH2Cl2 showed 36.59 37.78 respectively strains. Those CH3OH all greater than 50 μg/ml both H2O 21.48 As for extracts, 11.43 also alkaloid leaf 9.68 µg 3.56 With CH2Cl2, 6.62 was obtained 4.05 21.12 21.06 KI strain. more 32.73 aqueous 25.17 Key words: Medicinal plants, Niger, Malaria, Antiplasmodial activity, Alkaloids, Dichloromethane.